T.-C. Francis Pan

Ph. D. Candidate

Developmental Physiology and Genetics Research Group

Department of Biological Sciences

University of North Texas

Phone: 940-369-7629

E-mail: francispan@my.unt.edu

Address: 1155 Union Circle, # 305220, Denton, TX 76203

Research Interest:  Developmental and ecological physiology in vertebrates, especially aquatic vertebrates.  I am particularly interested in the respiratory, cardiovascular and osmoregulatory systems, and how they work together in response to environmental stimuli during development. 

 

Current Research:  I am working on development of the respiratory, cardiovascular and whole-body metabolic responses to hypoxia using the amphibian model, Xenopus laevis.  Physiology, especially developmental physiology of Xenopus laevis, a widely studied animal model in developmental biology, genomic and proteomic projects, is largely still unexplored due to their relatively small larval size and unsuitability for surgical processes.  The current research focuses on using non-invasive methods to measure cardio-ventilatory performance in early larvae.  The research result would link the current molecular knowledge with physiological systemic data.  Another focus of the project is how the developmental trajectory of hypoxic responses is affected by chronically hypoxic exposure, which is a useful tool to study regulation of all components within a control system, such as cardio-ventilatory control in response to fluctuating O₂ level in the environment.

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