STEP 8
Malate Dehydrogenase
 

In this step malate is oxidized to oxaloacetate, and a third NAD+ is reduced.  The reaction is not energetically favorable, but is pulled along by step 1. 
 
DG = ~0 kJ/mol
DGº' = +30 kJ/mol
Keq =  6.2 ·10-6


substrate: malate (CO2CH(OH)CH2CO2)
product: oxaloacetate (CO2COCH2CO2)

  Citric Acid Cycle
  Heather Shepheard
  Tainted by Chemical X
malate dehydrogenase