STEP 7
Fumarase

Fumarase catalyzes the trans-hydration of fumarate to L-malate.  The addition is stereospecific.  It is not known whether the intermediate is a carbonium or carbanion.
 
DG = ~0 kJ/mol
DGº' = -3.8  kJ/mol
Keq =  4.6


substrate: fumarate (CO2CHCHCO2)
product: malate (CO2CH(OH)CH2CO2)

  Citric Acid Cycle
  Heather Shepheard
  Tainted by Chemical X
fumarase